Energy metabolism

In addition to various organs and organ systems being affected by CFS, there may be a malfunctioning at a more basic level: the energy metabolism that occurs in each individual cell.

Researchers have posited that the lack of energy seen in CFS could be directly related to the poor energy output of individual cells.

When this idea was first presented to Dr. Komaroff about 10 years ago at an international scientific symposium, he was very skeptical.

He now feels, however, that there is “abundant evidence, from many studies from all over the world, in my view, that energy metabolism inside cells are adversely affected in CFS …  no one yet knows what is adversely affecting energy metabolism in the cells. But one very well known cause is viral infection.”