Telescoping CFS time—1989 

The first time Dr. Komaroff spoke to the Massachusetts CFIDS/ME & FM Association in the late 1980s, based on his developing knowledge of a then little-known illness, he offered the following view:

•    Infectious agents can probably trigger and perpetuate CFS—not in all cases, but in many.

•    The agents cannot be fully eradicated by the immune system. Instead, these agents that can cause CFS can be very different from each other in         many respects, but they will share the property of being resistant to full eradication by the immune system in a CFS patient.

•    There is evidence that CFS can follow a new infection.

•    It is also possible that in CFS different agents interact to cause CFS.

Dr. Komaroff gave his current view at the end of the lecture.