Rainbow at shoreline

The Massachusetts ME/CFS & FM Association, a 501(c)3 founded in 1985, exists to meet the needs of patients with ME (Myalgic Encephalomyelitis), CFS (Chronic Fatigue Syndrome) or FM (Fibromyalgia), their families and loved ones. The Massachusetts ME/CFS & FM Association works to educate health-care providers and the general public regarding these severely-disabling physical illnesses. We also support patients and their families and advocate for more effective treatment and research.

The recent multi-center study published on September 18, 2012 in mBio® (the online open-access journal of the American Society for Microbiology) concludes that no evidence of XMRV (xenotropic murine leukemia virus-related virus) and pMLV (polytropic murine leukemia virus) was found in patients with Chronic Fatigue Syndrome, disproving previous findings and hypothesis.

W. Ian Lipkin of Columbia University, a co-author on the study, reported "The bottom line is we found no evidence of infection with XMRV and pMLV. These results refute any correlation between these agents and disease." (Source: Neuroscience News, September 18, 2012).

Follow the instructions below to obtain access (free) to the full-text study.  

A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus (American Society for Microbiology, doi:10.1128/mBio.00266-12) Link provides access to multi-center study on XMRV and ME/CFS co-authored by Harvey J. Alter, Judy A. Mikovits, William M. Switzer, Francis W. Ruscetti, Shyh-Ching Lo, Nancy Klimas, Anthony L. Komaroff, Jose G. Montoya, Lucinda Bateman, Susan Levine, Daniel Peterson, Bruce Levin, Maureen R. Hanson, Afia Genfi, Meera Bhat, HaoQiang Zheng, Richard Wang, Bingjie Li, Guo-Chiuan Hung, Li Ling Lee, Stephen Sameroff, Walid Heneine, John Coffin, Mady Hornig and W. Ian Lipkin.

Once at the mBio® site, click on the right side bar for full text display or PDF of this study. This is an open-access (OA) article released on 09/18/2012 (under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

Notice about names

The Massachusetts ME/CFS & FM Association would like to clarify the use of the various acronyms for Chronic Fatigue Syndrome (CFS), Chronic Fatigue & Immune Dysfunction Syndrome (CFIDS) and  Myalgic Encephalomyelitis (ME) on this site. When we generate our own articles on the illness, we will refer to it as ME/CFS, the term now generally used in the United States. When we are reporting on someone else’s report, we will use the term they use. The National Institutes of Health (NIH) and other federal agencies, including the CDC, are currently using ME/CFS. 

Massachusetts ME/CFS & FM Association changed its name in July, 2018, to reflect this consensus.