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Fibromyalgia and Small Fiber Polyneuropathy PDF Print E-mail

Up to 60% of Fibromyalgia patients in some studies show evidence of Small Fiber Polyneuropathy (SFPN), a condition which shares many symptoms with Fibromyalgia and which may be treatable. Dr. Khosro Farhad spoke about this topic and reviewed recent research on SFPN at a public talk sponsored by the Massachusetts CFIDS/ME & FM Association on Nov. 14, 2015 at Newton-Wellesley Hospital, Newton, Massachusetts.

  • Dr. Khosro's slides are posted here.
  • The chart for diagnosing Fibromyalgia according to the 2011 criteria from the American College of Rheumatology is posted here.
  • A list of blood and other test to consider for diagnosing Small Fiber Polyneuropathy is posted here.

Disclaimer: There materials are provided only for convenience so that you can print them out and take them to discuss with your health care provider. 

Dr. Farhad has provided copies of the research articles that he mentioned in his talk.

Caro XJ et al, “Evidence of Abnormal Epidermal Nerve Fiber Density in Fibromyalgia, Clinical and Immunologic Implications,” Arthritis & Rheumatology: 66, No. 7 (July 2014): 1945–1954.

Kosmidis ML…Dalakas MC et al, “Reduction of Intraepidermal Nerve Fiber Density (IENFD) in the skin biopsies of patients with fibromyalgia: A controlled study,” Journal of the Neurological Sciences 347 (2014): 143–147.

Giannoccaro MP et al, “Small Nerve Fiber Involvement In Patients Referred For
Fibromyalgia,” Muscle Nerve 49 (2014): 757–759.

Oaklander AL, et al, “Objective evidence that small-fiber polyneuropathy underlies
some illnesses currently labeled as fibromyalgia,” Pain 154, No. 11 (November 2013).

Oaklander AL, et al, “Evidence of Small-Fiber Polyneuropathy in Unexplained,
Juvenile-Onset, Widespread Pain Syndromes,” Pediatrics 131 No. 4 (2013).

Uceyler N et al, “Small fibre pathology in patients with
fibromyalgia syndrome,” Brain 136 (2013): 1857–1867.

Soon we will be posting a summary of the talk with bibliography and a full video of the talk including the Question and Answer period. We will notify you via our Newsletter when these items are available.

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Study recruiting Fibromyalgia Patients - Boston area PDF Print E-mail

The Pain Management Center at Brigham & Women's Hospital is recruiting female Fibromyalgia patients for a study involving functional MRI imaging and cognitive behavioural therapy. See flyer for more information and to inquire about participating.

CDC Funding Update: The Importance of Lobbying PDF Print E-mail

A month ago, patient advocate Jennifer Spotila discovered that the U.S. Senate was proposing to zero-out the ME/CFS budget at the Centers for Disease Control and Prevention. Read what has happened since.

New Medicare payment for chronic care management PDF Print E-mail

Beginning January 1, 2015, Medicare pays separately under the Medicare Physician Fee Schedule CPT code 99490, for non-face-to-face care coordination services furnished to Medicare beneficiaries with multiple chronic conditions. Learn more.

Links to recent U.S. government reports on ME/CFS PDF Print E-mail

Institute of Medicine report:
Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness, February 10, 2015

National Institutes Of Health, Pathways to Prevention (P2P) Workshop report:
Advancing the Research on Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, December 9–10, 2014

Agency for Healthcare Research and Quality, Research Review (“Evidence review”):
Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, December 9, 2014

U.S. Food and Drug Administration, Patient-Focused Drug Development Initiative report:
Chronic Fatigue Syndrome and Myalgic Encephalomyelitis, September, 2013

National Institutes Of Health, State of Knowledge Workshop report:
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Research, April 7-8, 2011

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